The science behind your formulations

The unique formulations for your liquid supplement elixirs are based on clinical studies and research conducted at the world’s top research institutions. We work with a clinical advisory board to bring you what you deserve - supplements that work to adapt to your life’s milestones.

Why Freshness Matters

Just like food, vitamins degrade and become less potent over time - and this time is short! You want the freshest, individually sealed to reduce vitamins exposure to the air, light, and humidity before coming to your door.

1. Nhan, P. P., & Hoa, N. K. (2013). Effect of Light and Storage Time on Vitamin E in Pharmaceutical Products. British Journal of Pharmacology and Toxicology, 4(5), 176–180. Retrieved from http://maxwellsci.com/print/bjpt/v4-176-180.pdf

2. The success of a fortification program depends on a number of factors. (n.d.). Retrieved from https://www.dsm.com/content/dam/dsm/nip/en_US/documents/stability.pdf

3. Pignitter, M., Dumhart, B., Gartner, S., Jirsa, F., Steiger, G., Kraemer, K., & Somoza, V. (2014). Vitamin A Is Rapidly Degraded in Retinyl Palmitate-Fortified Soybean Oil Stored under Household Conditions. Journal of Agricultural and Food Chemistry, 62(30), 7559–7566. http://doi.org/10.1021/jf502109j

4. Yamada, K., Shimodaira, M., Chida, S., Yamada, N., Matsushima, N., Fukuda, M., & Yamada, S. (2008). Degradation of Vitamin B12 in Dietary Supplements. International Journal for Vitamin and Nutrition Research, 78(45), 195–203. http://doi.org/10.1024/0300-9831.78.45.195

5. Ribeiro, D. O., Pinto, D. C., Lima, L. M. T. R., Volpato, N. M., Cabral, L. M., & de Sousa, V. P. (2011). Chemical stability study of vitamins thiamine, riboflavin, pyridoxine and ascorbic acid in parenteral nutrition for neonatal use. Nutrition Journal, 10, 47. http://doi.org/10.1186/1475-2891-10-47

6. Perrier, E., Bonnet, I., Baron, M.-H., & Failloux, N. (2003). Quantitative Analysis of Vitamin A Degradation by Raman Spectroscopy. Applied Spectroscopy, Vol. 57, Issue 9, Pp. 1117-1122, 57(9), 1117–1122. Retrieved from https://www.osapublishing.org/as/abstract.cfm?URI=as-57-9-1117

7. Peleg, M., Normand, M. D., & Goulette, T. R. (2016). Calculating the degradation kinetic parameters of thiamine by the isothermal version of the endpoints method. Food Research International, 79, 73–80. http://doi.org/10.1016/j.foodres.2015.12.001

8. Peleg, M., Kim, A. D., & Normand, M. D. (2015). Predicting anthocyanins’ isothermal and non-isothermal degradation with the endpoints method. Food Chemistry, 187, 537–544. http://doi.org/10.1016/j.foodchem.2015.04.091

9. Verbeyst, L., Bogaerts, R., Van der Plancken, I., Hendrickx, M., & Van Loey, A. (2013). Modelling of Vitamin C Degradation during Thermal and High-Pressure Treatments of Red Fruit. Food and Bioprocess Technology, 6(4), 1015–1023. http://doi.org/10.1007/s11947-012-0784-y

10. Vieira, M. C., Teixeira, A. ., & Silva, C. L. . (2000). Mathematical modeling of the thermal degradation kinetics of vitamin C in cupuaçu (Theobroma grandiflorum) nectar. Journal of Food Engineering, 43(1), 1–7. http://doi.org/10.1016/S0260-8774(99)00121-1

11. Allwood, M. C., Stahlman, M., Chytil, F., Fujii, Y., Nishikawa, K., Ohrushi, N., … Kim, C. (1982). The influence of light on vitamin A degradation during administration. Clinical Nutrition (Edinburgh, Scotland), 1(1), 63–70. http://doi.org/10.1016/0261-5614(82)90006-1

Personalization Matters

Evidence shows vitamin metabolic pathways play a crucial role to preventing chronic disease and keeping you healthy.

1. Krishnan, A. V, Trump, D. L., Johnson, C. S., & Feldman, D. (2010). The role of vitamin D in cancer prevention and treatment. Endocrinology and Metabolism Clinics of North America, 39(2), 401–18, table of contents. http://doi.org/10.1016/j.ecl.2010.02.011

2. Krishnan, A. V, & Feldman, D. (2011). Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D. Annual Review of Pharmacology and Toxicology, 51, 311–36. http://doi.org/10.1146/annurev-pharmtox-010510-100611

3. Gocek, E., & Studzinski, G. P. (2009). Vitamin D and differentiation in cancer. Critical Reviews in Clinical Laboratory Sciences, 46(4), 190–209. http://doi.org/10.1080/10408360902982128

4. Cheung, F. S. G., Lovicu, F. J., & Reichardt, J. K. V. (2012). Current progress in using vitamin D and its analogs for cancer prevention and treatment. Expert Review of Anticancer Therapy, 12(6), 811–37. http://doi.org/10.1586/era.12.53

5. Bergman, P., Sperneder, S., Höijer, J., Bergqvist, J., Björkhem-Bergman, L., & Hagen, S. (2015). Low Vitamin D Levels Are Associated with Higher Opioid Dose in Palliative Cancer Patients – Results from an Observational Study in Sweden. PLOS ONE, 10(5), e0128223. http://doi.org/10.1371/journal.pone.0128223

6. Antioxidants as Part of Your Cancer Diet | Stanford Health Care. (n.d.). Retrieved September 5, 2017, from https://stanfordhealthcare.org/medical-clinics/cancer-nutrition-services/reducing-cancer-risk/antioxidants.html

7. Arem, H., Yu, K., Xiong, X., Moy, K., Freedman, N. D., Mayne, S. T., … Stolzenberg-Solomon, R. Z. (2015). Vitamin D Metabolic Pathway Genes and Pancreatic Cancer Risk. PLOS ONE, 10(3), e0117574. http://doi.org/10.1371/journal.pone.0117574

8. Zackular, J. P., Baxter, N. T., Iverson, K. D., Sadler, W. D., Petrosino, J. F., Chen, G. Y., … Engleman, E. G. (2013). The gut microbiome modulates colon tumorigenesis. MBio, 4(3), 541–546. http://doi.org/doi:10.1016/j.immuni.2016.08.008

9. Lagunova, Z., Porojnicu, A. C., Lindberg, F., Hexeberg, S., & Moan, J. (2009). The dependency of vitamin D status on body mass index, gender, age and season. Anticancer Research, 29(9), 3713–20. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/19667169

10. Treatment with All-trans Retinoic Acid Plus Tamoxifen and Vitamin E in Advanced Hepatocellular Carcinoma. (n.d.).

11. Nhan, P. P., & Hoa, N. K. (2013). Effect of Light and Storage Time on Vitamin E in Pharmaceutical Products. British Journal of Pharmacology and Toxicology, 4(5), 176–180. Retrieved from http://maxwellsci.com/print/bjpt/v4-176-180.pdf

12. Stout, J. R., Sue Graves, B., Smith, A. E., Hartman, M. J., Cramer, J. T., Beck, T. W., … Harris -RHarris, R. C. (n.d.). The effect of beta-alanine supplementation on neuromuscular fatigue in elderly (55–92 Years): a double-blind randomized study. http://doi.org/10.1186/1550-2783-5-21